NIDS® Multiplexed Rapid Assays

BACKGROUND
Handheld immunochromatographic assays offer many unique advantages over their bulky instrument-based counterparts: they are compact, easy to use, and have no power source requirements. Simple sample preparation and data interpretation have made them a preferred tool over gene-based assays for rapid field detection and point-of-care applications such as home pregnancy tests and cardiac marker detection. Due to the difficulty in controlling protein binding events at the nanoscale, protein-based assays often exhibit low sensitivity and unacceptably high false positive responses. ANP Tech's team has recently developed dramatically improved handheld assay (HHA) and microarray (HHMA) devices that can reliably detect the presence of biological agents at extremely low concentrations.

  1. ADVANTAGES:
    Enhances the sensitivity of existing antibody based assays up to 100 fold with
       5 fold less reagents
    Substantial reduction of false positive readings
    Enables effective use of extremely small amounts of reagent(s)
    Easy assay multiplexing and high throughput target screening (including proteomics)
    Improved lot-to-lot reproducibility
    Simple formulation and production processing
    EXAMPLE ASSAYS:
    B. anthracis bacterial spores
    Y. pestis bacteria
    Ricin toxin
    Botulinum toxin
    Smallpox
    Staphylococcus Enterotoxin B (SEB)
    V. cholerae
    C. burnetii
    F. tularensis
    E. Coli and E. Coli 0157
    Giardia
    Salmonella
    Cancer Biomarkers
    Cardiac/Heart related Biomarkers
    Cytokine Arrays (up to four in a single assay)

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