
NIDS® Multiplexed Rapid Assays
BACKGROUND
Handheld immunochromatographic assays offer many unique advantages
over their bulky instrument-based counterparts: they are compact,
easy to use, and have no power source requirements. Simple sample
preparation and data interpretation have made them a preferred tool
over gene-based assays for rapid field detection and point-of-care
applications such as home pregnancy tests and cardiac marker
detection. Due to the difficulty in
controlling protein binding
events at the nanoscale, protein-based assays often exhibit low
sensitivity and unacceptably high false positive responses. ANP
Tech's team has recently developed dramatically improved handheld
assay (HHA) and microarray (HHMA) devices that can reliably detect
the presence of biological agents at extremely low concentrations.
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ADVANTAGES:
Enhances the sensitivity of existing antibody
based assays up to 100 fold with
Substantial reduction of false positive
readings
Enables effective use of extremely small
amounts of reagent(s)
Easy assay multiplexing and high throughput
target screening (including proteomics)
Improved lot-to-lot reproducibility
Simple formulation and production processing
B. anthracis bacterial spores
Y. pestis bacteria
Ricin toxin
Botulinum toxin
Smallpox
Staphylococcus Enterotoxin B (SEB)
V. cholerae
C. burnetii
F. tularensis
E. Coli and E. Coli 0157
Giardia
Salmonella
Cancer Biomarkers
Cardiac/Heart related Biomarkers
Cytokine Arrays (up to four in a single assay)
5 fold less reagents
EXAMPLE ASSAYS: